MerriamWebster writes: to give a negative answer or reply to a question or request, or offer in a way that shows a negative response; used to introduce a statement that corrects an earlier statement; used as a function word to express the negative or an alternative choice or possibility; used to express negation, dissent, denial, or refusal.
Middle English, from Old English nā, from ne not + ā always; akin to Old Norse & Old High German ne not, Latin ne-, Greek nē- . First Known Use: before 12th century. Its synonyms are never, none, nothing, noway, nowise.
So uncomfortable (unbequem) and unpleasant (unangenehm) for Americas ears and eyes – no, negation, dissent, denial, refusal.
