Jefe means boss, and jefa is the female form. In Mexican slang, jefa also means mother.
Uno TV names it among the common Mexican words for a mother: “Una de las palabras comunes entre los mexicanos para referirse a su madre es ‘jefa'” (One of the common words Mexicans use for their mother is jefa). In April 2025, a column in Crónica described the same use as part of Mexican slang.